About me - Personally

I'm a German 👨‍👩‍👦‍👦 father and 💻 computer scientist / 🧬 bioinformatician who lives in Denmark. I keep my spirits up by 🏃‍♂️ running.

I love nature, and going for hikes over valleys and hills. I'm interested in all living things and understanding how they work.

I'm interested in sustainability, and solutions to tackle the climate crisis. I'm writing software for personal management of the own co2 footprint.

About me - Professionally

I like to use software and machine learning to discover structure in unstructured data. I have a 🎓 PhD in computer science - "unsupervised learning of biomedical data".

Contact / Profiles

• jonsnow posteo.de
• https://www.linkedin.com/in/wiwiec/
• https://github.com/wiwie
• libranet.de/profile/wiwiec

How I try to be more sustainable

• 100% wind power energy plan
• Tree donating/sponsoring

I'm contributing to folding@home

Tree donations/sponsoring

I am planning on continuously donating/sponsoring trees. That means I pay money to organizations that plant and care for trees/forests.

So far I donated the following:

• 9 trees at https://www.greenforestfund.de/ (donation of 1 tree monthly)

Our Electricity Plan

Recently we changed to an electricity plan at our energy provider that is 100% wind power (Energi Fyn - NaturEl).

The cost difference from our previous plan was comparably small (41 vs 37 øre/kWh), while this significantly reduces emissions.

While I disagree with calling the wind power plan emission free as Energi Fyn does (since production and maintenance for wind turbines should be incorporated into this value), average co2 emission levels of offshore wind power is denoted as 12g/kWh on Wikipedia - so are still pretty low.

Thus, assuming that Energi Fyn mostly uses offshore wind parks with a technological level causing median levels of emission, this still corresponds to a highly significant decrease in caused co2 emissions per kWh from 383g (our previous plan) to just 12g.

Under construction

This page is under construction.

Cytotoxic T-cell - David Goodsell

#science #art

Illustration by David S. Goodsell, RCSB Protein Data Bank; doi: 10.2210/rcsb_pdb/goodsell-gallery-026

This painting depicts the fusion of SARS-CoV-2 (magenta) with an endosomal membrane (green), releasing the viral RNA genome into the cell cytoplasm (blue), where it is beginning to be translated by cellular ribosomes to create viral polyproteins. The painting includes speculative elements that are designed highlight the process, most notably, multiple states of the viral spike protein are shown.

#science #art

David S. Goodsell, RCSB Protein Data Bank and Springer Nature; doi: 10.2210/rcsb_pdb/goodsell-gallery-025

This painting shows a cross section through SARS-CoV-2 surrounded by blood plasma, with neutralizing antibodies in bright yellow. The painting was commissioned for the cover of a special COVID-19 issue of Nature, presented 20 August 2020, and is currently in the collection of the Cultural Programs of the National Academy of Sciences.

It incorporates information from two cryoelectron microscopy studies that explore the shape and distribution of spikes and the nucleoprotein:
Yao H et al. (2020) Molecular architecture of the SARS-CoV-2 virus. bioRxiv preprint DOI: 10.1101/2020.07.08.192104
Ke Z et al. (2020) Structures, conformations and distributions of SARS-CoV-2 spike protein trimers on intact virions. bioRxiv preprint DOI: 10.1101/2020.06.27.174979

#science #art

Illustration by David S. Goodsell, RCSB Protein Data Bank; doi: 10.2210/rcsb_pdb/goodsell-gallery-019

This painting depicts a coronavirus just entering the lungs, surrounded by mucus secreted by respiratory cells, secreted antibodies, and several small immune systems proteins. The virus is enclosed by a membrane that includes the S (spike) protein, which will mediate attachment and entry into cells, M (membrane) protein, which is involved in organization of the nucleoprotein inside, and E (envelope) protein, which is a membrane channel involved in budding of the virus and may be incorporated into the virion during that process. The nucleoprotein inside includes many copies of the N (nucleocapsid) protein bound to the genomic RNA.

#science #art

His art combines two aspects that are really dear to me, science and art. I love it!

Would love to see something like this about topics of #computationalbiology as well.

I would like it if a scientist comes to work, sees the sun shining through one of these pieces, and feels inspired and valued, if a non-scientist appreciates them for their artistic qualities, becomes curious and wants to know more, and if young people look at these and start asking questions – especially questions that we never thought of and to which we don’t know the answers.

Nice, #hitman3 going to be released for pc tomorrow. Reviews read positive. Would definitely feel like playing that stealthy, lethal kind of game again. Though I'll have to wait for 6 months first until it's available for a reasonable 50% (max) of the 60€ it costs at release.

my son (3y) watches a lot of clips about trucks, busses, cars, stuff like that on YT Kids. I'd like to avoid using it though for multiple reasons.

An obvious one is not wanting to feed data silos, another is that after watching three German/English videos he always ends up on some random one with a foreign language (most often Russian). So we can't really understand and double check what he watches.

I'm thinking about somehow creating my own collection of such video clips and self-hosting them, maybe playing them with JellyFin (which we are already using). but that would require enough videos so he doesn't get bored after 5 minutes. also, it'd probably require some kind of app that has a "recommendation" system (though self-hosted) that recommends a list of similar videos after he has finished the last one. I don't think JellyFin has that though - AFAIK it has a random play feature.

Any experience with something like this? What approaches do fellow parents use? Are there options, or are you biting the bullet and use YT or other data silos anyways?

And if you use such a self-hosted approach, where do you get the clips from? buy them on DVD/BR?

#kids #selfhosted #clips #busses #trucks #cars

"Die Hütte im Wald" - Ivan Shishkin (1832 - 1898)

#art #forest #lodge

I experienced death in my family from a comparably early age. I tried to learn from it and act such that I feel ready when someone then eventually dies.

But I never am ready. No matter how much i try. I am always left with the feeling, that I did not sufficiently make use of the time and that I did not properly say fairwell.

By now I'm inclined to conclude that that is just how it is. I can never be ready for it when someone leaves. And that is also the whole point of death: If you could be ready for it beforehand, that would just be a demonstration of how little our connections mattered. But they do matter - a lot.

#death #neverready

wireless charging with efficiency below a minimal threshold should be forbidden. A pitty, that it's starting to be integrated everywhere, even in Intel NUCs. WTF.

In my tests, I found that wireless charging used, on average, around 47% more power than a cable.

- https://debugger.medium.com/wireless-charging-is-a-disaster-waiting-to-happen-48afdde70ed9

A minor bit of comfort traded for an environmental toll that can be expected to be large. It depends on the efficiency of the wireless charger, but the cheap ones have quite low efficiency of around 60-70% and those are probably the ones that will be most widely adopted.

Some voices say the wear on phone parts such as the USB / charger port of the phone when cable charging also has to be factored into this calculation. But seriously, the wear for my last 3 phones was really small and only really had any consequences after years of usage. This compared against inefficient wireless charging everyday for years can't even come close.

#WirelessCharging #environmental #disaster
Wireless Charging Is a Disaster Waiting to Happen